There are some ideas, in fact. They are not very well developed, though, because such research is very expensive, and even the very educated people on this side fiercely fighting the idea that extending people's life is a good thing.
Until the general public accepts the necessity of the age-related research, there won't be any effective mechanism for age reversion.
NIH yearly budget is 35B dollars. Half of that they spend on cancer research, the other half divides between the other diseases. Age research is a tiny fraction of this budget.
Until NIH spends at least 1/3 of their annual budget on fighting aging, there won't be any significant progress.
No, my point is that I personally am very afraid of death, and would fight death from the selfish reasons.
People who support the notion of death seem not to constantly fear it themselves, but view it as something hypothetical, that they wouldn't have to face themselves in the near future (likely several decades).
Telomeres are only one part of the equation, and they likely natural mechanism for controlling the cell differentiation. My understanding they resemble natural breaks that prevent cells to divide uncontrollably where they shouldn't.
I doubt they are the primary cause of ageing.
I prefer the theory explaining ageing as an epigenome misregulation that David Sinclair describes.
Ageing is natural and harmful. Hunger is natural and harmful. Earthquakes, hurricanes, plaque are natural and harmful. We should mercilessly fight all of those, and ensure either of those maladies cause people to die.
If there is a tiger chasing you, wouldn't you try to escape or fight? Or just give up and let the tiger eat you? It is natural, tiger also want to eat, right?
Today's medicine is focused to treat the diseases, refusing to admit that people at 70-80 years old die not from disease, but from the old age.
Everybody but a few enthusiasts refuse to treat ageing instead of cancer or heart diseases. People in general refuse to treat ageing as a disease, thinking it is something natural.
I would not want a couple more miserable years on earth, I want a few million years of a healthy young life.
Until the general public accepts the necessity of the age-related research, there won't be any effective mechanism for age reversion.
NIH yearly budget is 35B dollars. Half of that they spend on cancer research, the other half divides between the other diseases. Age research is a tiny fraction of this budget.
Until NIH spends at least 1/3 of their annual budget on fighting aging, there won't be any significant progress.