Not sure what you mean by over-eager. Patients are only intubated and placed on mechanical ventilation when they will die otherwise. There is a step wise increase in ventilatory support in these cases, starting at a nasal cannula, then increasing to face mask, then a positive pressure (CPAP) mask, and then if they are still hypoxic or hypercarbic - intubation is the next step.
VAP (ventilator associated pneumonia) is a known morbidity of mechanical ventilation. ICU protocols are much improved these days to combat it (oral hygiene, suctioning, early extubation protocols etc).
I am a vascular surgeon, and have many patients in the ICU constantaly. #6 confuses me - the original operating surgeon should be a constant through the patient’s stay. And while the ICU doctor might be the captain while the patient is in the ICU, the original surgeon is the general. He has complete control and should dominate the patient’s care. While the surgeon can not be bedside 24/7, they or someone from their team should “round” at least once daily on these ICU patients, talking to family, checking catheters and tubes, reviewing medicines, checking wounds.
Not getting the attention it deserves. CT scans with IV contrast are critical for trauma, cancer staging, emergency general surgery, orthopedics - everything. Having to ration it at all is a big deal. And IV contrast is used for more than just CT scans.
I am a vascular surgery trainee. Myself and others rely every day on IV contrast to do our jobs. We were told today the hospital has a two week supply left - and the production side could take 6 weeks to catch up. Scary stuff.
The problem the paper is addressing is fibrin micro clots, which occurs in long Covid. This also occurs in acute Covid. The treatment is similar - anti coagulation. We (doctors) knew this from the beginning (1). Chill out bubba.
I am an expert in the field of clotting mechanics (US NIH funded research / vascular surgery fellow). Not sure why they chose TEG to monitor coagulation status - it does not reflect well changes from any of the drugs used in the study.
It would be interesting to see the results broken down by gender - females respond much differently to aspirin and have less of a survival benefit than males (don’t get me started, many of the initial trials in the 60’s with aspirin were done with mostly males).
Also, in my own research - we have found that aspirin “softens” clots which allows platelets to squeeze pathological clots to smaller sizes, which allows more recannalization of thrombosed vessels and thus less ischemia - would be interesting to see if that same MOA happens here.
As an engineer the PCL seemed like foreign territory as it was in the other side of campus. Thus it was a nice place to go and think, especially in the map room, it was a magic place.
They mention in the paper that the Dark Ages power spectrum would require a 100,000 dipole antenna array, seems like we are far from that.
Full disclosure brain fart - dark side of the moon still gets sun light (duh, right?), this basic fact had me scratching my head with regards to power source for an embarrassing amount of time.
Agree for Mars - this tech will translate well into other areas of need in hostile environments - like agriculture, mining, large scale manufacturing etc.
I think it’s a great idea to build mud huts on another planet where labor is scarce, machine energy is under different constraints, and certain resources are “unlimited”.
But this approach for building a house on Earth to house humans seems way off the bell curve of potential to scale.
Yes true, but brick and other base material like it is very strong and support fixtures to attach ducting, pipes, cables - I’m not sure you can drill brackets into this mud and safely secure an AC duct or conduit.
Yet another example of the over-hype of “3D Printing”. Yes it’s neat that they collected some local dirt, mixed it with some non-locally sourced water and binder, and poured it into an extruder run on some kind of non locally sourced energy, then sprayed it with some protective coating - it baffles me that people see this as a possible mainstream building technique. Running electrical, plumbing, air conditioning etc through this structure is doable but much harder, as the expectations of these niceties have evolved with modern construction and need easy access and hiding with things like dry wall.
This almost reads as an onion article with the headline “brilliant scientists figure out how to overcomplicate the construction of mud huts similar to our earliest human ancestors”.
I was a medical student with Cohn and Frazier in 2012 at Texas Heart - it was an awesome experience. Every day we would either do a heart transplant or peel a heart mate II out of a box and implant that. I remember sitting in Cohn’s office and him doing magic tricks, lighting things on fire, or making us laugh. Frazier would always have a book in his lab coat, usually something in Russian, to read at his leisure. Truly visionary people. They have a good TED talk where you can get a good idea of their personalities.