There isn't a single philosophical meaning. You are probably thinking of libertarian free will..furthering Obviously false because determinism isn't obviously true.
Popperians claim that positive justification is impossible.
Popperians claim.Induction doesn't exist (or at least , matter in science)
Popper was prepared to consider the existence of Propensities objective.probabilities, whereas Bayesians, particularly those who follow Jaynes believe in determinism and subjective probability.
Popperian refutation is all or nothing, whereas Bayesian negative information is gradual.
In Popperism, there can be more than one front running or most favoured theory, even after the falsifiable ones have been falsified, since there aren't quantifiable degrees of confirmation.
For Popper and Deutsch, theories need to be explanatory, not just predictive. Bayesian confirmation and disconfirmation only target prediction directly -- if they are achieving explanation or ontological correspondence , that would be the result of a convenient coincidence.
For Popperians, the construction of good theoretical conjectures is as important as testing them. Bayesian seem quite uninterested in where hypotheses come from.
For Deutschians, being hard-to-vary is the preferred principle of parsimony. For Yudkuwsians, it's computation complexity.
Error correction as something you actually do. Popperians like to put forward hypotheses that are easy to refute. Bayesians approve theoretically of "updating", but dislike objections and criticisms in practice.
(Long term) prediction is basically impossible . More Deutsch than Popper -- DD believed that the growth and unpredictability of knowledge . The creation of knowledge is so unpredictable and radical that long term predictions cannot be made. Often summarised to "prediction is impossible". Of course , Bayesians are all about prediction --but the predictive power of Ates tends only to be demonstrated in you models, where the ontology isn't changing under your feet. Their AI I predictions are explicitly intuition based.
Optimism versus Doom. Deutsch is highly optimistic that continuing knowledge creation will change the world for the better (a kind of moral realism is a component of this). Yudkowsky thinks advanced AI is our last invention and will kill us all.*
Several different definitions are being bandied about. If you think of reduction as understanding a material system in terms of its components, biology is now reductionist, having abandoned vitalism.