I assume the larger portion of what's "untenable" is "short commutes"; spending multiple hours of unpaid personal time in a car per day just driving to and from work so that you can have the place you sleep be affordable is a huge downside of a lot of in-person jobs that used to be taken as more of a default pre-pandemic, before so many places showed "yeah we could let you work from home but we just don't want to".
The downsides of an open floor plan can be at least partially countered by headphones, but there's much less that you can do on an individual level to make up for having that much of your personal time locked up in pure transit.
The downsides of an open floor plan can be at least partially countered by headphones, but there's much less that you can do on an individual level to make up for having that much of your personal time locked up in pure transit.