You can't win this by being reactive. It's the same dynamic as with terrorism. No government can keep terrorism under control, if it just responds to terrorist attacks. You need special task force which infiltrates and basically terrorize terrorists, so that they don`t have time and resources to plan for new attacks. Same with mining, if all miners have to care about is just how to bypass your heuristics, they will always outnumber and outsmart you, but if they will also have to spend time to constantly patch their own code to keep blockchain and mining pools running, meanwhile maintaining consensus that mining shouldn't be dropped all together, to avoid constant proactive attacks on network, only then you stand a chance.