75-125 is an actual trip. Anything less than that you're not going to get the full psychedelic experience. We can debate the effects of microdosing, but 100-150ug has been a gold standard for decades for a reason.
Everyone is saying meditation etc, I would disagree. A major part is the ability to put this experience in motion/action which I find counterintuitive to meditation. Quite frankly no, I do not think it is replicable to be able to turn off the filters in which are responsible for keeping the raw data to a manageable level, that is much different than increasing your sensitivity through deprivation. Alteration of brain chemistry may be simulated in the future, but there is no replacement today.
Hash rate is 90+m terahash and increasing, good luck R&Ding the chips and obtaining enough to achieve. Retail pricing is around 3k per 50 TH/s, and that is just for hardware.
I'm just arguing that it would make more sense to start at 80-110-140-170 etc because below that is placebo.