Many in the research community realised the model was wrong a long time ago. This is a great read about the reasons why: 'How not to study a disease: the story of Alzheimer’s.' by Karl Herrup.
A small number of readily measured physiological traits may be used clinically to evaluate therapeutics designed to slow aging and extend healthy life. Playing computer games associates with slower ageing.
I tried this with a question for an area I know well. It's pretty impressive but missed some key references.
I'd love to see limitations like this quantified and clearly flagged. Otherwise there's a danger that people may the assume results are definitive, and this could have the opposite outcome to that intended (much time spent working on something only to disocver it's been done already).