Polylaminin, a drug considered capable of reversing spinal cord injury(www1.folha.uol.com.br)
www1.folha.uol.com.br
Polylaminin, a drug considered capable of reversing spinal cord injury
https://www1.folha.uol.com.br/internacional/en/scienceandhealth/2025/09/groundbreaking-brazilian-drug-considered-capable-of-reversing-spinal-cord-injury-presented-in-sao-paulo.shtml
13 comments
Paper:
https://journals.plos.org/plosone/article?id=10.1371/journal...
I think it's actually this one, or perhaps a new one after it:
https://www.medrxiv.org/content/10.1101/2024.02.19.24301010v...
https://www.medrxiv.org/content/10.1101/2024.02.19.24301010v...
I find this part most interesting:
"Three participants (2, 7, 8) regained motor control. i.e., converted to AIS C or D, at the 1-month examination. Other three (4, 5, 6) converted to grade C after 3 months. In the present study we observed that, in contrast to the expected baseline conversion of 15%, 75% (6/8) of the participants regained voluntary motor control after polylaminin treatment. If we consider only those participants that reached discharge, the proportion increases to 100% (6/6)."
That paper is an in vitro demonstration whereas the OP article seems to imply they tested on actual patients?
Yes, it was tested on patients. @ bfdrummond on Instagram was the first one - he is now almost 100% recovered
Do we know of other patients?
Sometimes drug and medical device companies will gag patients with non-disparagement agreements, while letting the success stories post freely on social media to promote their product/procedure/etc.
Sometimes drug and medical device companies will gag patients with non-disparagement agreements, while letting the success stories post freely on social media to promote their product/procedure/etc.
Published: October 8, 2014
More recent work indexed in Google Scholar: https://scholar.google.com/citations?hl=en&user=TVozLNoAAAAJ...
More recent work indexed in Google Scholar: https://scholar.google.com/citations?hl=en&user=TVozLNoAAAAJ...
This is fantastic news.
A good friend of mine spent years doing research at Caltech in basically trying to bridge the severed part of the spinal column with electrodes. In mice that is.
The department got lots of $ from the Christopher & Dana Reeve Foundation to help them in said research.
A good friend of mine spent years doing research at Caltech in basically trying to bridge the severed part of the spinal column with electrodes. In mice that is.
The department got lots of $ from the Christopher & Dana Reeve Foundation to help them in said research.
More details: https://ensaiosclinicos.gov.br/news/331
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