The title is a little misleading. Surely it should read Using only CoffeeScript, Titanium, Node, Socket.io and a Chrome extension...
In fact, the title has very little to do with the actual article (which to be fair uses the same misleading title). Should be "Building a Chrome To Mobile extension using JavaScript only".
It's a shame because the actual project looks cool, just wish some more details were included.
Haven't really built anything beyond simple test apps, but from what I've seen it could be a really great tool.