Not exactly your experience, but using a single (non-4k) external monitor is slightly painful for me with my MBP. It sometimes takes ~10 seconds for my display to work after plugging it in, with lots of intermittent flickering as the OS "figures it out". And afterwards, the menu bar on the external is a bit glitchy looking on the right side until I click on it. With my other laptop running Fedora the experience is much faster/cleaner.
Not a big deal, but just thought I'd mention that macOS isn't exactly perfect when it comes to external monitors.
I have a problem with directions / general spatial awareness that sounds similar to what you have. I have a hard time plotting a route to a known location in my head in the city I've lived in for 10+ years, but strangely have no problem getting there once I start driving/biking/walking (depending on how familiar I am with the destination, obviously). I've made it a point to study maps and randomly test whether or not I can point out cardinal directions when I'm out and about and that seems to have helped a bit, but I have a hard time navigating new and unfamiliar places. Truly big cities like Chicago are impossible to navigate. I don't know what I'd do without GPS.
I am, although I use the Xfce version. Back in the day, before I learned to program, I used distributions like Arch, Slackware, Gentoo, etc. that generally required manual configuration and knowledge of the system and Linux in general. I realize this seems backwards, but these days I'd rather spend my time developing things than configuring my workstation. My interest in computers has moved from administration to creation, and using an operating system that takes care of the former allows me to better spend my time doing the latter.
That said, in light of Mint's issues I'm seriously considering moving back to Xubuntu or some other disto that has Xfce as a first class citizen. I'd be interested in suggestions.
Not a big deal, but just thought I'd mention that macOS isn't exactly perfect when it comes to external monitors.