I can relate! It's gotten to a point where I'm seriously considering if it's worth it at all. Sometimes I feel outright depressed after having had some drinks the night before, to a point where the observer in my mind is shocked at the dark thoughts I'm having.
I have a fructose malabsorption and most drinks I enjoy (wine, cocktails) do have a huge amount of this sugar in them. I wonder if this might be one of the reasons it's messing with my mood so much - I recall my gastro-doc saying something along the line that high fructose intake can lead to depression/symptoms of depression.