"Former Goldman Sachs commodities chief Jeffrey Currie said this week the real reason the oil price had not returned meaningfully above $100 a barrel in the past few weeks was not a sign of supply - which has been severely constricted by the near-closure of the Strait of Hormuz - being plentiful, but rather of what he called "capital aversion"."
Realistically, without data from a large testset that compares this thoroughly to Samtools (and others?), I wouldn't touch this.
Note to the OP: specify a focus please? short, long, mega-long read and bacterial, human, small plant or large plant genome? Alignment heuristics and performance differ significantly across those axes.
I would argue that craftsmanship includes a thorough understanding and cognitive model of the code. And, as far as I understand it, these agents are syntactic wonders but can not really understand anything. Which would preclude any sort of craftsmanship, even if what they make happens to be well-built.
So, I respect the entrepeneurship and technical skills to make this. Well done!
That being said, this is insane.
Maintaining your social network is a skill, just like being able to swim, doing math, being able to hold a good conversation, being able to code or cook or do your taxes.
The "promise" and "illusion" of silicon valley is that all problems (including and maybe even especially social ones) can be solved with technology. This is not true.
Having to use your brain to think about things is definitely painful. It also has incredibly good long-term effects -- and also negative short-term effects because it costs energy. It's similar to eating well, regularly exercising and other aspects of taking care of yourself.
Making sure you can remember to think about other people is not a problem -- it's a REALLY valuable skill that is gradually disappearing.
It's kind of weird that Romania has done so well, given that amount of turmoil in Romanian politics and Romania in general in the last 20 years.
Basically, it went up for Romania because they got access to the EU market (in terms of both exports and remittances) starting in 2007 and that helped, _despite_ everything else that went on. So.. kind of a win for Romania and the EU, I guess.
Idiotic and massively overlooks/underestimates how complex biology is.
What about beneficial and neutral but important bacteria and viruses? "Air" is actually a complex soup of all types of things. This like applying HCl to a skin infection.