I have tried doing the several times in past because of chromes arrogant and monopoly like attitude on forcing feature addition or removal
But browsing works better and faster in chrome and most consumer base blindly use chrome
If you want to build a extension with a user base you will have to use chrome
If you want your website to work properly it must satisfy chrome first
I installed nginx using macports didn't have uwsgi params module.
I tried finding solution on Google couldn't find.
Deleted macports installed nginx via brew