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dbbolton

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dbbolton
·3 ปีที่แล้ว·discuss
Unless you have access to coca leaves, your recipe is likely to taste like generic cola.

Coca-Cola has special privileges to import raw coca leaves. They extract the cocaine (which is then sold for pharmaceutical use). The mostly-cocaine free extract is then used to flavor their cola. AFAIK Coca-Cola is the only entity in the US allowed to do this, so it is unsurprising that other cola brands taste significantly different.
dbbolton
·12 ปีที่แล้ว·discuss
Hypothetically if a person did experience myalgia as a direct result of drinking Earl Grey tea and their proposed mechanism is accurate, the treatment would probably involve K+ channel opener with a lower K_d (higher affinity) than the culprit bergapten, perhaps Diazoxide.
dbbolton
·12 ปีที่แล้ว·discuss
Unfortunately fluorosis can be a bit more serious than just some marks on your teeth.

In severe cases of skeletal fluorosis, patients can experience pain/damage to the bones and joints.

https://en.wikipedia.org/wiki/Skeletal_fluorosis
dbbolton
·12 ปีที่แล้ว·discuss
Because the proposed mechanism has nothing to do with histamine or immune response. Such a K+ channel blocker should hypothetically have the same effect in the vast majority of the general population.
dbbolton
·12 ปีที่แล้ว·discuss
Excessive black tea consumption can also cause fluorosis. It's quite difficult to say just how much tea one would have to drink to cause any symptoms though.

Bottom line, moderation is usually a good idea.