DuckDB also runs in Excel, by the way, via the free xlwings Lite add-in that you can install from the add-in store. It’s using the Python package and allows to write scripts, custom functions, as well as use a Jupyter-like notebook workflow.
Pyodide powers xlwings Lite, a free Excel add-in that you can install from Excel’s add-in store with a single click. It outperforms Microsoft’s official Python in Excel solution in every coceivable way: price, privacy, speed, can install packages, can access the internet, can access local files, doesn’t have a usage quota, can automate Excel and create native UDFs. See https://lite.xlwings.org
Have you tried the CSP build of AlpineJS? It takes the code out of the template into a proper JS file, no unsafe-eval. Isn't state management mostly handled on the backend when you use AlpineJS?